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Proteomics > Which service should I request? > Glycan / Glycoprotein analysis

Glycan / Glycoprotein analysis


General description

We provide support for many glycan and glycoprotein analysis workflows, including the project discussion, the mass spectrometry, and the data analysis.
Glycosylation is known as one of the most important and common post-translational modifications across all kingdoms and plays an essential role in nearly all aspects of biology. Examples of supported applications include the identification of glycoproteins (i.e., as indicators of diseases), the profiling of glycans in different type of treated samples, and the identification of N-glycans and of glycosylated peptides (i.e., N-linked glycosylation occupancy).

List of applications and services

FGCZ offers the following types of services for the analysis of glycans, glycopeptides and glycoproteins

Applications (examples) Which service to order
Identify potential glycoprotein candidates. It does not include enrichment Identification of glycoproteins
Identify N-glycosylation sites. It includes glycan release with PNGase F (w/o heavy water))N-linked glycans site occupancy
Site-specific glycosylation (glycopeptide analysis)Glycopeptide analysis
Characterization of released N-linked glycans Characterization of N-‚Äčlinked glycans
Quantification of free and released mammalian monosaccharides Monosaccharide analysis - mammalian
Determination of sialic acid contentSialic acid quantification (please contact us before ordering)
Analysis of released O-linked glycans and other glycans Other (please contact us before ordering)


If you don't find what you are looking for, or you are interested in special applications, please contact us at proteomics at fgcz.ethz.ch



Created by paolo. Last Modification: 2023-04-05 14:20 by paolo.