Proteomics > Which service should I request? > Interaction Proteomics

Interaction Proteomics

General description

Proteins seldom function in isolation but are embedded in protein networks. These networks are often highly dynamic and a direct reflection of a cells functional state. Probing a proteins social context can therefore be exceedingly informative and ultimately lead to a better understanding of its biology. Mass spectrometry-based solutions enable the examination of a protein’s functional context. The methods are unbiased, at a proteome-scale, and applicable to in vivo /ex vivo experiments.

We offer full packages service including project discussion, pilot preliminary experiments, mass spectrometry and bioinformatics data analysis.
Examples of interaction proteomics applications are affinity proteomics (pull-downs) and proximity labelling (i.e., BioID, TurboID, APEX).

List of applications and services

FGCZ offers the following types of MS-based analyses for Interaction Proteomics

Applications (examples) Which service to order
Identification of interaction partners by affinity purification mass spectrometry (AP-MS)Affinity Purification - AP MS
Identification of interaction partners by proximity labelling (BioID, TurboID, APEX) ProximityLabeling

In some cases, we also offer:
Applications (examples) Which service to order
Custom data analysis on FGCZ datasets Bioinformatics analysis (only in special cases - please contact us before ordering)

If you don't find what you are looking for, or you are interested in special applications, please contact us at proteomics at fgcz.ethz.ch

Created by paolo. Last Modification: 2023-03-24 12:10 by paolo.