Proteomics > Which service should I request? > Interaction Proteomics

Interaction Proteomics

General description

Proteins seldom function in isolation but are embedded in protein networks. These networks are often highly dynamic and a direct reflection of a cells functional state. Probing a proteins social context can therefore be exceedingly informative and ultimately lead to a better understanding of its biology. Mass spectrometry-based solutions enable the examination of a protein’s functional context. The methods are unbiased, at a proteome-scale, and applicable to in vivo /ex vivo experiments.

We offer full packages service including project discussion, pilot preliminary experiments, mass spectrometry and bioinformatics data analysis.
Examples of interaction proteomics applications are affinity proteomics (pull-downs) and proximity labelling (i.e., BioID, TurboID, APEX).

List of applications and services

FGCZ offers the following types of MS-based analyses for Interaction Proteomics

Applications (examples)	Which service to order
Identification of interaction partners by affinity purification mass spectrometry (AP-MS)	Affinity Purification - AP MS
Identification of interaction partners by proximity labelling (BioID, TurboID, APEX)	ProximityLabeling

In some cases, we also offer:

Applications (examples)	Which service to order
Custom data analysis on FGCZ datasets	Bioinformatics analysis (only in special cases - please contact us before ordering)

If you don't find what you are looking for, or you are interested in special applications, please contact us at proteomics at fgcz.ethz.ch

Quick links

• How to order an analysis?
  • Follow our order instructions
• Questions?
  • Check our FAQs page or contact us at proteomics at fgcz.ethz.ch
• Prices
  • The prices for the most common proteomics services can be found here.