MetaCore Information Resource

MetaCore is a software for pathway analysis and similar functional analyses. It has a proprietary manually curated database of gene/protein functions and interactions. The FGCZ can set up user accounts on demand. Please contact sequencing at fgcz.ethz.ch

• MetaCore is started from here: http://portal.genego.com

Help

• MetaCore has a useful online help that is available after login
• On youtube there is a series of tutorials from Clarivatee Analytics about using MetaCore. Please note that we have only a license for MetaCore. Not for Key Pathway Advisor, etc.
• Recommended tutorials are
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  • see the list MetaCore Quick Start Videos

Important:

• When uploading experimental data please use the columns "log2 Ratio" and "pValue" from the results generated with Sushi! Please make sure that the "log2 Ratio column comes first. Otherwise the data will not be well displayed in MetaCore
• Do remove genes where the value in the FDR column is "NA". Those genes have very low counts and have not been considered as expressed.
• For additional instructions do contact sequencing at fgcz.ethz.ch

Hints if you do not work with Human/Mouse/Rat..

MetaCore is able to also work for organisms which are usually not supported. This works via an orthologue mapping with ENTREZ-GeneIDs..
Therefore it is absolutely necessairy to upload EntrezGeneIDs (uniprot allows mapping of Uniprot Accessions or IDs to EntrezGeneIDs)